Abstract: The oil and gas development in the Luzhou Area of the Sichuan Basin has entered a mature stage, charactericed by a large number of abandoned wells with high warter-cut. Research on the redevelopment of its geothermal resources holds strategic significance for achieving the region's "dual carbon"goals. The study area located on the Indosinian Luzhou-Kaijiang paleo-uplift, hosts the Qixia-Maokou Formation of the Permian, recognized as the region's most significant karst-type geothermal reservoir. This formation exhibits the typical features of a basin-type, stratabound, medium- to low-temperature geothermal system. Drawing on geological, seismic, drilling, and logging data, this study analyzes the reservoir-caprock assemblages, temperature distribution, and structural characteristics of the area. Findings reveal that geothermal heat accumulation in the paleo-uplift zone results from a combined mechanism of heat conduction, concealed fault-driven heat convection, and thermal radiation reflection. A volumetric approach was used to quantitatively assess geothermal resource reserves. The results indicate that crustal uplift from the Indosinian Luzhou paleo-uplift, together with fault development caused by Himalayan and Yanshan tectonic movements, facilitated the accumulation of deep geothermal fluids in the Luzhou area, forming a distinctive tectonic heat accumulation system. The estimated geothermal resources in the Qixia-Maokou Formation total 2.894×10²⁰ J, equivalent to 9.87×10⁹ tons of standard coal, demonstrating substantial potential for geothermal development in the region.